UVAS Library

Your cart is empty.

Your search returned 2 results. Subscribe to this search

Not what you expected? Check for suggestions
Unhighlight Highlight
|
1.
No cover image available
Burden Of Respiratory Illness Related To Influenza Among Oupatient And Inpatients Healthcare Facility Centers District Sheikhupura

by Ayesha Mukhtar (2014-VA-1052) | Dr. Mamoona Chaudhry | Prof. Dr. Mansur-ud-din Ahmad | Dr. Shafqat Fatima Rehmani.

Material type: book Book; Literary form: not fiction Publisher: 2017Dissertation note: Influenza is a highly contagious, acute illness in humans. Influenza viruses have negative-sense RNA genomes and are placed in the Orthomyxoviridae family grouped into three types A, B and C on the basis of the internal nucleocapsid or the matrix protein. Droplet and airborne are the most common modes of transmission. In Humans infection appears to be direct or indirect exposure to infected person or infected live or dead poultry or contaminated environments.Globally the annual attack rate with influenza viruses ranges between 5 to10% in adults and 20- 30 % in children. The WHO estimates that 3-5 million cases of severe influenza illness occur every year resulting in 250,000 to 500,000 deaths worldwide, with most influenza deaths occurring among adults over 65 years of age. Influenza is the cause of outpatient visits and inpatient hospitalization among population of District Sheikhupura. A prospective study for duration of 3 months (September to october) was performed in Tehsil Muridke District Sheikhupra. Population of Tehsil Muridke is 4, 52,009. We selected Tehsil headquarter hospital randomly as sentinel sites .Our Target population was cases of ILI and SARI. All cases of influenza like illness (ILI) or severe acute respiratory illness (SARI) who meets the inclusion & exclusion criteria was enrolled. Data was obtained by the face to face interview. A detail investigation form was filled after taking written consent form. Throat swab was collected from patient. The sample was stored at -70°C for further laboratory procedure. We will use Reverse transcriptase polymerase chain reaction (RT-PCR) for detection of type of the influenza virus. RT-PCR allows viral template RNA to be reversed transcribed producing complementary DNA (cDNA) which can then be amplified and detected. So in our Study we used RT-PCR for influenza virus detection. Data analyzed by using SPSS software with 95% confidence interval. Chi-square test used to measure the association of risk factors (age, sex, occupation, exposure, healthcare worker, travelling etc) and the rate of morbidity and mortality was calculated by using standard formulae. We identified ILI and SARI cases associated with outpatients and inpatients & also provided data to identify and monitor groups at high risk for influenza and will measure trends in morbidity and mortality attributable to influenza. Availability: Items available for loan: UVAS Library [Call number: 2805-T] (1).

Place hold Add to cart
2.
No cover image available
Cross Sectional Survey Of Avian Infleunza In Poultry Butchers Of Sentinel Live Bird Markets In Lahore District

by Gul Naz Namat (2014-VA-1120) | Dr. MamoonaChaudhary | Dr. Hassan Mushtaq | Dr. Shafqat Fatima Rehmani.

Material type: book Book; Literary form: not fiction Publisher: 2017Dissertation note: 6.1 Background: Influenza is a highly contagious, acute illness in humans. Influenza viruses have negative-sense RNA genomes and are placed in the Orthomyxoviridae family grouped into three types A, B and C on the basis of the internal nucleocapsid or the matrix protein. Droplet and airborne are the most common modes of transmission. In Humans infection appears to be direct or indirect exposure to infected live or dead poultry or contaminated environments, such as live bird markets. 6.2 Hypothesis: Avian influenza virus is prevalent in poultry butchers working in live bird markets with domestic and pet, wild, exotic birds. 6.3 Parameter/Methodology: A cross sectional survey of poultry butchers in Lahore was conducted in order to determine seroprevalence of avian influenza Disease. A target population was the poultry butchers/retailers in the District Lahore. A study population was the apparently healthy butchers in Lahore. A sample of 300 butchers was collected. Blood sample from apparently healthy butchers was collected from brachial veins as described in WHO (2010). Three ml blood was collected in the syringe and was allowed to clot to separate serum. Collected sera was stored in freezer at -70°C for further laboratory analysis. Data was gathered by simple random sampling technique. A total of 300 samples were collected. Haemagglutinationinhibition (HI) test applied to detect antibodies sensitivity. The test was followed as described by WHO (2013). 6.4 Statistical Design: The weighted proportion estimate with 95% Cl (confidence intervals) of the overall seroprevalence was computed by using R-software. Logistic regression was conducted to estimate the effect of each study variable on the outcome. 6.5 Outcomes: Out of 300 blood samples of butchers of sentinel live bird markets, 171 blood samples are sero positive for H9 virus after HI Testing. The sero prevalence of H9 virus in butchers of live bird markets is found to be 57 %. The results of H5 and H7 are found to be negative. In univariable analysis, following risk factors which were significant as per criteria of selection in current study (p-value < 0.25); Education, Age, Smoking, Sticks smoke/day, Years of smoking, Having chronic disease, Birds sold/day, Keep birds at home, Access of stray dogs, Access of stray cats, Wash instruments after slaughtering, Do not clean cutting boards, Wearing of aprons.Multivariate analysis determined one factor i-e having birds other than broiler as significant factor having p-value < 0.001. Availability: Items available for loan: UVAS Library [Call number: 2804-T] (1).

Place hold Add to cart

Implemented and Maintained by UVAS Library.
For any Suggestions/Query Contact to library or Email:rehana.kousar@uvas.edu.pk Phone:+91 99239068
Website/OPAC best viewed in Mozilla Browser in 1366X768 Resolution.